Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161745 | 0.91 | GRM2 (0.51) | GRM2SIGMAR1 | |
| SCHEMBL14540825 | 0.84 | GRM2 (0.55) | GRM2SIGMAR1KMT2A | |
| SCHEMBL14168504 | 0.84 | GRM2 (0.55) | GRM2F10FADS1 | |
| SCHEMBL9550258 | 0.84 | GRM2 (0.55) | GRM2F10FADS1 | |
| SCHEMBL9550256 | 0.83 | GRM2 (0.40) | GRM2HTR6F10FADS1 | |
| SCHEMBL31192184 | 0.83 | ALDH1A1 (0.46) | GRM2KMT2A | |
| SCHEMBL30162780 | 0.83 | ALDH1A1 (0.46) | GRM2KMT2A | |
| SCHEMBL24852630 | 0.83 | ALDH1A1 (0.46) | GRM2KMT2A | |
| SCHEMBL24794868 | 0.83 | GRM2 (0.40) | GRM2HTR6F10FADS1 | |
| SCHEMBL6266797 | 0.82 | GRM2 (0.57) | GRM2FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529621-B1 | Nickel-based metal-organic framework as catalyst for chemical fixation of CO2 in oxazolidinone synthesis | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11529621-B1 | Nickel-based metal-organic framework as catalyst for chemical fixation of CO2 in oxazolidinone synthesis | BTF3, FZD7, POF1B | GRM2 2372/4885SIGMAR1 3881/4885KMT2A 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.