SCHEMBL24795035

SCHEMBL24795035

C[Si](C)(C)O[Si](C)(C)CCCNc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.39
KCNH3 Q9ULD8 5/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
KDM1A O60341 1/20 0.35
EHMT2 Q96KQ7 1/20 0.35
RCOR1 Q9UKL0 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
ICMT O60725 1/20 0.35
LMNA P02545 1/20 0.35
PPARG P37231 1/20 0.34
DRD4 P21917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10400318 0.93 MAPT (0.57) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL974893 0.84 MAPT (0.55) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL976197 0.81 ALDH1A1 (0.52) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL18417832 0.80 ALDH1A1 (0.64) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL31687255 0.78 MAPT (0.52) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL49467 0.77 MAPT (0.55) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL31687729 0.77 MAPT (0.50) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL31687723 0.77 MAPT (0.50) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL31687718 0.77 MAPT (0.50) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2
SCHEMBL31687257 0.76 MAPT (0.53) ALDH1A1MAPTL3MBTL1KCNH3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-08-03 US disclosed
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 ALDH1A1 1437/4885MAPT 4498/4885L3MBTL1 552/4885
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 ALDH1A1 1428/4885MAPT 4514/4885L3MBTL1 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.