SCHEMBL24796000

SCHEMBL24796000

O=C(CSCC(=O)NC1CC1)NCCN1C(=O)CNC1=O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ TSHR P16473 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ PDE7A Q13946 2/20 0.37
▸ LMNA P02545 2/20 0.37
▸ HPGD P15428 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ RECQL P46063 1/20 0.36
▸ KMT2A Q03164 3/20 0.35
▸ HTT P42858 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ GLA P06280 1/20 0.33
▸ MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21389356 0.95 HPGD (0.43) L3MBTL1TSHRALDH1A1RAB9APDE7A
SCHEMBL24796113 0.84 TSHR (0.51) L3MBTL1TSHRALDH1A1PDE7ALMNA
SCHEMBL24795923 0.81 L3MBTL1 (0.44) L3MBTL1TSHRALDH1A1RAB9ALMNA
SCHEMBL24796282 0.80 HPGD (0.47) L3MBTL1TSHRALDH1A1RAB9ALMNA
SCHEMBL24796631 0.80 HTT (0.44) L3MBTL1ALDH1A1RAB9ALMNAHPGD
SCHEMBL24795942 0.79 ATM (0.44) L3MBTL1ALDH1A1RAB9ALMNAHPGD
SCHEMBL21389225 0.79 HPGD (0.46) L3MBTL1TSHRALDH1A1RAB9ALMNA
SCHEMBL24795907 0.79 HPGD (0.43) L3MBTL1ALDH1A1RAB9ALMNAHPGD
SCHEMBL24796403 0.78 L3MBTL1 (0.40) L3MBTL1TSHRALDH1A1RAB9ALMNA
SCHEMBL24796659 0.78 L3MBTL1 (0.40) L3MBTL1TSHRALDH1A1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR L3MBTL1 2127/4885TSHR 140/4885ALDH1A1 3305/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR L3MBTL1 2161/4885TSHR 142/4885ALDH1A1 3367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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