SCHEMBL24796399

SCHEMBL24796399

CC1(C)SC(=O)N(CCNC(=O)CSCC(=O)NC2CC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ HPGD P15428 5/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ LMNA P02545 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ TSHR P16473 2/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ HSD17B10 Q99714 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21389146 0.85 GAA (0.37) L3MBTL1ALDH1A1RAB9AKMT2ALMNA
SCHEMBL26746202 0.85 ALDH1A1 (0.32) L3MBTL1ALDH1A1RAB9AKMT2ASMN1; SMN2
SCHEMBL24796397 0.85 CYP1A2 (0.36) L3MBTL1ALDH1A1RAB9AKMT2ASMN1; SMN2
SCHEMBL24796307 0.78 HPGD (0.42) L3MBTL1ALDH1A1RAB9AHPGDKMT2A
SCHEMBL24795923 0.78 L3MBTL1 (0.44) L3MBTL1ALDH1A1RAB9AHPGDKMT2A
SCHEMBL24795920 0.78 L3MBTL1 (0.40) L3MBTL1ALDH1A1RAB9AHPGDKMT2A
SCHEMBL21389327 0.77 HPGD (0.41) L3MBTL1ALDH1A1HPGDKMT2ALMNA
SCHEMBL24796662 0.77 HPGD (0.40) L3MBTL1ALDH1A1RAB9AHPGDKMT2A
SCHEMBL24796661 0.77 HPGD (0.43) L3MBTL1ALDH1A1RAB9AHPGDKMT2A
SCHEMBL24795951 0.76 L3MBTL1 (0.38) L3MBTL1ALDH1A1RAB9AHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR L3MBTL1 2161/4885ALDH1A1 3367/4885RAB9A 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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