Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23671169 | 0.85 | TDP1 (0.35) | — | |
| SCHEMBL31009000 | 0.80 | NUDT1 (0.34) | — | |
| SCHEMBL22576011 | 0.80 | NUDT1 (0.34) | — | |
| SCHEMBL24349548 | 0.79 | HMGCR (0.33) | HMGCRAR | |
| SCHEMBL22576679 | 0.77 | NUDT1 (0.37) | — | |
| SCHEMBL2018538 | 0.77 | SYK (0.38) | — | |
| SCHEMBL22065925 | 0.76 | TLR8 (0.32) | — | |
| SCHEMBL21719183 | 0.76 | TLR8 (0.30) | — | |
| SCHEMBL21718914 | 0.75 | ALDH1A1 (0.38) | HMGCRAR | |
| SCHEMBL1661164 | 0.75 | GABRA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728223-B1 | CYCLOHEXYL ACID TRIAZOLE AZINES AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-28 | — | — | EP | disclosed |