Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045604 | 0.82 | SMN1; SMN2 (0.41) | LTA4HCHEK2KDM4EGLAHTT | |
| SCHEMBL11059897 | 0.80 | KDM4E (0.56) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11045319 | 0.80 | KDM4E (0.56) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL27975171 | 0.76 | VNN1 (0.44) | KDM4EKMT2AHIF1ATDP1L3MBTL1 | |
| SCHEMBL21384000 | 0.76 | FEN1 (0.44) | LTA4HHRH3FEN1HTR3AHRH4 | |
| SCHEMBL11049864 | 0.75 | MAPK1 (0.49) | HRH3KDM4EKMT2ATDP1L3MBTL1 | |
| SCHEMBL24799023 | 0.75 | GCK (0.33) | LTA4HCHEK2HRH3TRPA1F2 | |
| Hydrochloric Acid SCHEMBL21384130 | 0.74 | FEN1 (0.43) | LTA4HHRH3FEN1HTR3AHRH4 | |
| SCHEMBL23863736 | 0.73 | HRH3 (0.39) | CHEK2HRH3TRPA1HRH4 | |
| SCHEMBL21241330 | 0.72 | PDE9A (0.41) | LTA4HHRH3TRPA1SMN1; SMN2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728223-B1 | CYCLOHEXYL ACID TRIAZOLE AZINES AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-28 | — | — | EP | disclosed |