Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045319 | 0.86 | KDM4E (0.56) | SMN1; SMN2KDM4EGLAHTTKMT2A | |
| SCHEMBL11059897 | 0.86 | KDM4E (0.56) | SMN1; SMN2KDM4EGLAHTTKMT2A | |
| SCHEMBL24798653 | 0.82 | LTA4H (0.37) | SMN1; SMN2KDM4EGLAHTTKMT2A | |
| SCHEMBL11049864 | 0.81 | MAPK1 (0.49) | KDM4EKMT2ATDP1L3MBTL1HDAC6 | |
| SCHEMBL11061422 | 0.78 | P4HTM (0.59) | SMN1; SMN2KDM4EGLAHTTKMT2A | |
| SCHEMBL27975171 | 0.76 | VNN1 (0.44) | KDM4EKMT2AHIF1ATDP1L3MBTL1 | |
| SCHEMBL21394688 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HDAC6RAB9ANPC1GCK | |
| SCHEMBL21241330 | 0.72 | PDE9A (0.41) | SMN1; SMN2GCKLTA4H | |
| SCHEMBL21384000 | 0.72 | FEN1 (0.44) | LTA4H | |
| SCHEMBL11047112 | 0.72 | P4HTM (0.56) | SMN1; SMN2KDM4EGLAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |