Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19704094 | 1.00 | SCN1A (0.32) | SCN1ASCN2ASCN3ASIGMAR1 | |
| SCHEMBL24799370 | 0.92 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL29296034 | 0.81 | LMNA (0.31) | SCN1ASCN2ASCN3A | |
| SCHEMBL24742875 | 0.71 | — | — | |
| SCHEMBL16659569 | 0.70 | NAMPT (0.32) | — | |
| SCHEMBL19122812 | 0.70 | NAMPT (0.32) | — | |
| SCHEMBL12457864 | 0.68 | NCF1 (0.34) | — | |
| SCHEMBL25621149 | 0.68 | NCF1 (0.30) | — | |
| SCHEMBL20007952 | 0.68 | NCF1 (0.34) | — | |
| SCHEMBL12457818 | 0.68 | NCF1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108659-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |