Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377388 | 0.90 | KMT2A (0.57) | KMT2AMEN1OPRM1OPRD1NPC1 | |
| SCHEMBL19377587 | 0.85 | DRD2 (0.38) | KMT2AMEN1OPRD1NPC1RAB9A | |
| SCHEMBL24800025 | 0.84 | ALDH1A1 (0.38) | KMT2ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL19377014 | 0.83 | MEN1 (0.39) | KMT2AMEN1DRD2HTR2AHTR2C | |
| SCHEMBL19377183 | 0.83 | HSD17B10 (0.48) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL19377317 | 0.83 | HSD17B10 (0.48) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL19377210 | 0.83 | HSD17B10 (0.48) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL19377329 | 0.82 | DRD2 (0.42) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL19377320 | 0.82 | NAMPT (0.44) | DRD2HTR2AHTR2CDRD3HTR6 | |
| SCHEMBL24801213 | 0.82 | ROCK2 (0.38) | KMT2AMEN1DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |