SCHEMBL3851276

SCHEMBL3851276

NC(=O)C[C@@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
USP2 O75604 1/20 0.46
SLCO1B1 Q9Y6L6 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 1/20 0.44
KDM4E B2RXH2 2/20 0.34
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599666 1.00 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL15754347 1.00 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL26091297 1.00 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
Hydrochloric Acid SCHEMBL28610464 0.98 LMNA (0.46) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL7510580 0.95 LMNA (0.55) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL2480041 0.84 USP2 (0.39) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL26092953 0.84 USP2 (0.39) LMNAL3MBTL1USP2SLCO1B1TDP1
Xylitol SCHEMBL4750185 0.84 LMNA (0.59) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL29620322 0.82 LMNA (0.50) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL21014430 0.82 LMNA (0.50) LMNAL3MBTL1USP2SLCO1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10494452-B2 Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof JIUZHITANG CO., LTD. (CN) 2019-12-03 US claimed
EP-2985298-B1 LOW-MOLECULAR-WEIGHT FUCOSYLATED GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF JIUZHITANG CO LTD (CN) 2019-09-25 EP claimed
US-20160060364-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) 2016-03-03 US claimed
EP-2985298-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF Kunming Institute of Botany Chinese Academy of Sciences (CN) 2016-02-17 EP claimed
CN-111484565-B Sweet wormwood polysaccharide, preparation method thereof and application thereof in preparation of anticomplement medicines 复旦大学 2022-06-07 CN disclosed
CN-111484565-A Sweet wormwood polysaccharide, preparation method thereof and application thereof in preparation of anticomplement medicines 复旦大学 2020-08-04 CN disclosed
US-10494452-B2 Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof JIUZHITANG CO., LTD. (CN) 2019-12-03 US disclosed
EP-2985298-B1 LOW-MOLECULAR-WEIGHT FUCOSYLATED GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF JIUZHITANG CO LTD (CN) 2019-09-25 EP disclosed
EP-2010510-B1 USE OF A LACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY L'ORÉAL (FR) 2017-06-07 EP disclosed
EP-2007746-B1 USE OF A GALACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY ORÉAL L (FR) 2016-08-31 EP disclosed
US-20160060364-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) 2016-03-03 US disclosed
EP-2985298-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF Kunming Institute of Botany Chinese Academy of Sciences (CN) 2016-02-17 EP disclosed
US-20140220081-A1 USE OF A GALACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY L'OREAL (FR) 2014-08-07 US disclosed
US-8217164-B2 Use of a lactose-derived C-glycoside compound as an agent for activating and regulating cutaneous immunity L'OREAL (FR) 2012-07-10 US disclosed
US-20090305997-A1 USE OF A GALACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY L'OREAL (FR) 2009-12-10 US disclosed
US-20090275525-A1 USE OF A LACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY L'OREAL (FR) 2009-11-05 US disclosed
EP-2049125-A2 TREATMENT OF CANCER WITH 2-DEOXYGALACTOSE Landau, Bernard R. (US) 2009-04-22 EP disclosed
US-20070248556-A1 Administration of C-glycoside compounds for activating and regulating cutaneous immunity L'OREAL (FR) 2007-10-25 US disclosed
WO-2007098183-A2 TREATMENT OF CANCER WITH 2-DEOXYGALACTOSE LANDAU BERNARD R (US) 2007-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305997-A1 USE OF A GALACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY GALK1, GLA, LGALS2 LMNA 3700/4885L3MBTL1 3598/4885USP2 3341/4885
US-20070248556-A1 Administration of C-glycoside compounds for activating and regulating cutaneous immunity NFATC1, CCL11, CCR7 LMNA 4534/4885L3MBTL1 4434/4885USP2 2741/4885
US-20160060364-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF FUCA2, PLG, FUCA1 LMNA 1208/4885L3MBTL1 2651/4885USP2 1744/4885
US-20140220081-A1 USE OF A GALACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY GALK1, GLA, LGALS2 LMNA 3877/4885L3MBTL1 3818/4885USP2 3217/4885
US-20090275525-A1 USE OF A LACTOSE-DERIVED C-GLYCOSIDE COMPOUND AS AN AGENT FOR ACTIVATING AND REGULATING CUTANEOUS IMMUNITY GLA, FUT6, LCT LMNA 1393/4885L3MBTL1 1459/4885USP2 2859/4885
US-10494452-B2 Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof FUCA2, PLG, FUCA1 LMNA 1208/4885L3MBTL1 2651/4885USP2 1744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.