SCHEMBL7176980

SCHEMBL7176980

Nc1ccc(C(c2ccc(N)cc2)C(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.61
ESR2 Q92731 4/20 0.61
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 7/20 0.41
TDP1 Q9NUW8 5/20 0.41
KIF11 P52732 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 4/20 0.39
HIF1A Q16665 3/20 0.39
ALOX15 P16050 2/20 0.39
CA3 P07451 1/20 0.39
THRB P10828 1/20 0.39
CA6 P23280 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA14 Q9ULX7 1/20 0.39
TP53 P04637 2/20 0.36
TSHR P16473 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6925377 0.91 ESR1 (0.52) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL9296352 0.89 ALDH1A1 (0.54) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL24800705 0.87 ALDH1A1 (0.56) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL28413968 0.84 ESR1 (0.45) ESR1ESR2MAPTALDH1A1TDP1
SCHEMBL28409924 0.82 APP (0.45) ESR1ESR2MAPTALDH1A1TDP1
SCHEMBL22337433 0.81 ESR1 (0.42) ESR1ESR2ALDH1A1TDP1CYP3A4
SCHEMBL3645937 0.79 MEN1 (0.42) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL21825334 0.77 ESR1 (0.41) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL22326114 0.76 ESR1 (0.64) ESR1ESR2ALDH1A1TDP1HIF1A
SCHEMBL3682920 0.76 ESR1 (1.00) ESR1ESR2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435185-B2 Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane CENTRAL GLASS COMPANY, LIMITED (JP) 2025-10-07 US disclosed
US-12351685-B2 Polyamide acid, polyimide, optical film, display device and production methods thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2025-07-08 US disclosed
US-12129338-B2 Thermosetting resin composition for semiconductor package, prepreg and metal clad laminate using the same LG CHEM, LTD. (KR) 2024-10-29 US disclosed
US-12091510-B2 Thermosetting resin composite and metal clad laminate using the same LG CHEM, LTD. (KR) 2024-09-17 US disclosed
EP-3750957-B1 THERMOSETTING RESIN COMPOSITE FOR METAL CLAD LAMINATE AND METAL CLAD LAMINATE LG CHEMICAL LTD (KR) 2024-07-03 EP disclosed
US-11848263-B2 Multilayered printed circuit board, method for manufacturing the same, and semiconductor device using the same LG CHEM, LTD. (KR) 2023-12-19 US disclosed
US-20230323030-A1 Polyamide, Polyamide-Imide, Derivatives of These, Optical Film, Display Device, and Production Methods Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2023-10-12 US disclosed
US-20230323030-A1 Polyamide, Polyamide-Imide, Derivatives of These, Optical Film, Display Device, and Production Methods Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2023-10-12 US disclosed
US-20230323030-A1 Polyamide, Polyamide-Imide, Derivatives of These, Optical Film, Display Device, and Production Methods Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2023-10-12 US disclosed
WO-2023190187-A1 MALEIMIDE COMPOUND, MALEAMIC ACID COMPOUND, CURABLE COMPOSITION, CURED PRODUCT, ELECTRONIC DEVICE, METHOD FOR PRODUCING MALEIMIDE COMPOUND AND METHOD FOR PRODUCING MALEAMIC ACID COMPOUND セントラル硝子株式会社 2023-10-05 WO disclosed
WO-2020162411-A1 POLYAMIDE ACID, POLYIMIDE, OPTICAL FILM, DISPLAY DEVICE AND PRODUCTION METHODS OF THOSE セントラル硝子株式会社 2020-08-13 WO disclosed
WO-2020060265-A1 MULTI-LAYER PRINTED CIRCUIT BOARD, METHOD FOR MANUFACTURING SAME, AND SEMICONDUCTOR DEVICE USING SAME 주식회사 엘지화학 2020-03-26 WO disclosed
WO-2020060197-A1 THERMOCURABLE RESIN COMPOSITION FOR COATING METAL THIN FILM, RESIN-COATED METAL THIN FILM USING SAME, AND METAL FOIL LAMINATE 주식회사 엘지화학 2020-03-26 WO disclosed
US-20200048440-A1 THERMOSETTING RESIN COMPOSITION FOR COATING METAL THIN FILM AND METAL LAMINATE USING THE SAME LG CHEM, LTD. (KR) 2020-02-13 US disclosed
US-20190276661-A1 RESIN COMPOSITION FOR SEMICONDUCTOR PACKAGE, PREPREG AND METAL CLAD LAMINATE USING THE SAME LG CHEM, LTD. (KR) 2019-09-12 US disclosed
US-20190270881-A1 RESIN COMPOSITION FOR SEMICONDUCTOR PACKAGE, PREPREG, AND METAL CLAD LAMINATE USING THE SAME LG CHEM, LTD. (KR) 2019-09-05 US disclosed
EP-3480245-A1 RESIN COMPOSITION FOR SEMICONDUCTOR PACKAGE, PREPREG USING SAME, AND METAL FOIL LAMINATED PLATE LG Chem, Ltd. (KR) 2019-05-08 EP disclosed
EP-3480244-A1 RESIN COMPOSITION FOR SEMICONDUCTOR PACKAGE, PREPREG USING SAME, AND METAL FOIL LAMINATED PLATE LG Chem, Ltd. (KR) 2019-05-08 EP disclosed
US-20030054184-A1 Optical element, method for the production thereof and optical module HITACHI CHEMICAL CO., LTD. (JP) 2003-03-20 US disclosed
EP-1117102-A2 Method of manufacturing material for forming insulating film JSR Corporation (JP) 2001-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351685-B2 Polyamide acid, polyimide, optical film, display device and production methods thereof PUF60, PARG, TET3 ESR1 3908/4885ESR2 4490/4885MEN1 2303/4885
US-12435185-B2 Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane NAF1, FXR1, AFF1 ESR1 4737/4885ESR2 3744/4885MEN1 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.