Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211661 | 0.84 | MAPT (0.63) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL5975744 | 0.79 | MAPT (0.67) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL24800990 | 0.78 | SREBF2 (0.44) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL24800992 | 0.76 | APP (0.43) | APPMAPTRAB9AMEN1KMT2A | |
| SCHEMBL11224731 | 0.76 | APP (0.76) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL31022177 | 0.76 | PIK3CD (0.69) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL2381840 | 0.76 | PIK3CD (0.69) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL4949115 | 0.75 | APP (0.58) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL61917 | 0.73 | APP (1.00) | APPMAPTKDM4ERAB9AMEN1 | |
| SCHEMBL16739391 | 0.73 | TERT (0.49) | APPMAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271676-A1 | INDOLE-SUBSTITUTED QUINOLINES AND THEIR COMBINATION WITH PLK1 INHIBITORS FOR THE TREATMENT OF CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2022-12-29 | — | — | WO | disclosed |