Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.56 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346256 | 0.76 | LIPE (0.44) | LIPEKDM4EPOLBMAPTRECQL | |
| SCHEMBL27230222 | 0.76 | LIPE (0.44) | LIPEKDM4EPOLBMAPTRECQL | |
| SCHEMBL27207984 | 0.76 | LIPE (0.44) | LIPEKDM4EPOLBMAPTRECQL | |
| SCHEMBL16320521 | 0.75 | LIPE (0.57) | LIPEKDM4EPOLBMAPTL3MBTL1 | |
| SCHEMBL29958132 | 0.74 | LIPE (0.57) | LIPEMAPTL3MBTL1ENPP2FFAR1 | |
| SCHEMBL20371015 | 0.74 | LIPE (0.57) | LIPEMAPTL3MBTL1ENPP2FFAR1 | |
| SCHEMBL12083566 | 0.74 | PTGER1 (0.56) | PTGER1PTGER4PTGER3PTGER2KDM4E | |
| SCHEMBL29956215 | 0.73 | NPC1 (0.57) | LIPEKDM4EENPP2 | |
| SCHEMBL24803085 | 0.73 | TTR (0.40) | MMEACEKDM4EAPAF1POLB | |
| SCHEMBL4329673 | 0.73 | SMPD1 (0.56) | LIPEKDM4EENPP2SMPD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270143-A1 | BORONO-PHENYLALANINE DERIVATIVE | ステラファーマ株式会社 | 2022-12-29 | — | — | WO | disclosed |