Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958132 | 1.00 | LIPE (0.57) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1163386 | 0.88 | LIPE (0.57) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL29954144 | 0.88 | LIPE (0.57) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL16320521 | 0.85 | LIPE (0.57) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL4329673 | 0.83 | SMPD1 (0.56) | LIPEMAPK1RXRAENPP2HTT | |
| SCHEMBL906202 | 0.83 | NPC1 (0.57) | LIPEENPP2SMN1; SMN2 | |
| SCHEMBL29956215 | 0.83 | NPC1 (0.57) | LIPEENPP2SMN1; SMN2 | |
| SCHEMBL25526392 | 0.83 | MAPT (0.47) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL28606699 | 0.83 | LIPE (0.68) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL544428 | 0.81 | LIPE (0.53) | LIPEMAPTRXRARXRBENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| CN-117062813-A | Polycyclic compound and application thereof | 四川汇宇制药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-20230151159-A1 | COMPOUND FOR FORMING HARDMASK, HARDMASK COMPOSITION INCLUDING THE COMPOUND, AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE USING THE HARDMASK COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-05-18 | — | — | US | disclosed |
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2019-10-31 | — | — | US | disclosed |
| WO-2018127928-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2018-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | BCHE, DDT, DBF4 | LIPE 1435/4885MAPT 2085/4885MAPK1 4199/4885 |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1A, TET1, KDM3A | LIPE 2103/4885MAPT 138/4885MAPK1 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.