Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446918 | 0.82 | LMNA (0.59) | SMN1; SMN2KDM4EALDH1A1HTTHSD17B10 | |
| SCHEMBL24802523 | 0.82 | NPSR1 (0.48) | NPSR1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL14074043 | 0.74 | HTT (0.50) | SMN1; SMN2KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL23479904 | 0.74 | HTT (0.47) | NPSR1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL21960820 | 0.73 | NPSR1 (0.49) | NPSR1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL24803365 | 0.72 | KDM4E (0.39) | SMN1; SMN2KDM4EALDH1A1USP2MAPK1 | |
| SCHEMBL22305679 | 0.72 | GAA (0.50) | NPSR1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL10196841 | 0.72 | GAA (0.40) | NPSR1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7926564 | 0.72 | GAA (0.44) | KDM4EHTTHSD17B10MEN1KMT2A | |
| SCHEMBL11356386 | 0.71 | PTGS2 (0.42) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |