Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481479 | 0.94 | PPARG (0.40) | LTB4RLTB4R2LMNAMAPTGAA | |
| SCHEMBL2481053 | 0.93 | LTB4R (0.42) | LTB4RLTB4R2LMNAMAPTGAA | |
| SCHEMBL2478205 | 0.89 | KMT2A (0.39) | LMNAMAPTGAAPOLBALDH1A1 | |
| SCHEMBL2484165 | 0.89 | MAPT (0.43) | LMNAMAPTGAAPOLBALDH1A1 | |
| SCHEMBL2484613 | 0.88 | PPARG (0.42) | LTB4RLTB4R2LMNAMAPTGAA | |
| SCHEMBL2507751 | 0.87 | LMNA (0.42) | LMNAMAPTGAAPOLBALDH1A1 | |
| SCHEMBL2479128 | 0.86 | PPARG (0.41) | LTB4RLTB4R2LMNAMAPTGAA | |
| SCHEMBL2481849 | 0.86 | LMNA (0.41) | LMNAMAPTGAAPOLBALDH1A1 | |
| SCHEMBL2502670 | 0.86 | LMNA (0.41) | LMNAMAPTGAAPOLBALDH1A1 | |
| SCHEMBL2511694 | 0.85 | LMNA (0.41) | LMNAMAPTGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | LTB4R 2692/4885LTB4R2 1987/4885LMNA 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.