Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024271 | 0.69 | — | — | |
| SCHEMBL24804355 | 0.69 | — | — | |
| SCHEMBL999429 | 0.64 | ADRA1A (0.32) | — | |
| SCHEMBL9260664 | 0.63 | GRIA1 (0.42) | — | |
| SCHEMBL8088424 | 0.61 | — | — | |
| SCHEMBL2918384 | 0.60 | CRBN (0.50) | AR | |
| SCHEMBL16353275 | 0.59 | CRBN (0.40) | — | |
| SCHEMBL9267374 | 0.59 | KDR (0.46) | — | |
| SCHEMBL17621553 | 0.58 | MAP3K12 (0.32) | — | |
| SCHEMBL24927818 | 0.57 | ADAMTS4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425649-A | Pyrazole derivatives as KRAS mutein inhibitors | 诺华股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| WO-2022269508-A1 | PYRAZOLYL DERIVATIVES AS INHIBITORS OF THE KRAS MUTANT PROTEIN | NOVARTIS AG (CH) | 2022-12-29 | — | — | WO | disclosed |