Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | GAA | P10253 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CDC7 | O00311 | 2/20 | 0.49 |
| ▸ | PLK4 | O00444 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | MARK3 | P27448 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540565 | 0.79 | MAPT (0.65) | MAPTGAAALDH1A1SMN1; SMN2AGTR1 | |
| SCHEMBL246611 | 0.74 | ALDH1A1 (0.47) | MAPTGAAALDH1A1SMN1; SMN2AGTR1 | |
| SCHEMBL14108123 | 0.74 | FAAH (0.57) | MAPTGAAALDH1A1SMN1; SMN2AGTR1 | |
| SCHEMBL246915 | 0.72 | ALDH1A1 (0.54) | MAPTGAAALDH1A1SMN1; SMN2AGTR1 | |
| SCHEMBL15559125 | 0.70 | MAPT (0.54) | MAPTGAAALDH1A1SMN1; SMN2AGTR1 | |
| SCHEMBL1083471 | 0.69 | SMN1; SMN2 (0.65) | MAPTGAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4111390 | 0.69 | SMN1; SMN2 (0.75) | MAPTALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7748140 | 0.68 | NPC1 (0.73) | MAPTGAAALDH1A1SMN1; SMN2AGTR1 | |
| Fluoride SCHEMBL11790867 | 0.68 | SMN1; SMN2 (0.63) | MAPTGAAALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11158946 | 0.68 | SMN1; SMN2 (0.63) | MAPTALDH1A1SMN1; SMN2HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000036-A1 | TREATMENT OF ABNORMALITIES OF GLUCOSE METABOLISM WITH AN ANTAGONIST OF INHIBITOR OF DIFFERENTIATION 1 | GARVAN INSTITUTE OF MEDICAL RESEARCH (AU) | 2012-01-05 | — | — | WO | disclosed |