SCHEMBL24807409

SCHEMBL24807409

CC(C)CC(SF)c1ccc(C(C)C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
IDO1 P14902 2/20 0.35
USP5 P45974 1/20 0.35
TYR P14679 2/20 0.34
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
HTT P42858 2/20 0.32
NOTUM Q6P988 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849598 0.81 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3IDO1USP5
SCHEMBL104124 0.68 TYR (0.58) IDO1USP5TYRLMNANPC1
SCHEMBL8960196 0.67 CTSK (0.38) ALDH1A1PYCR1
SCHEMBL18873296 0.66 TYR (0.41) IDO1USP5TYRLMNAMEN1
SCHEMBL11389632 0.65 TAAR1 (0.42) SLC6A3LMNAMEN1KMT2AHTT
Water SCHEMBL11726962 0.65 TYR (0.55) IDO1USP5TYRLMNANPC1
Ammonia Solution, Strong SCHEMBL7550588 0.65 TYR (0.55) IDO1USP5TYRLMNANPC1
Water SCHEMBL29278796 0.65 TYR (0.55) IDO1USP5TYRLMNANPC1
SCHEMBL28912214 0.65 TYR (0.55) IDO1USP5TYRLMNANPC1
SCHEMBL6203905 0.65 TYR (0.55) IDO1USP5TYRLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022271970-A1 METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING Singular Genomics Systems, Inc. (US) 2022-12-29 WO disclosed