SCHEMBL248078

SCHEMBL248078

Nc1ccc(C(=O)OC(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
LMNA P02545 4/20 0.54
F2 P00734 1/20 0.54
CYP3A4 P08684 3/20 0.52
CYP1A2 P05177 2/20 0.52
MAOA P21397 1/20 0.52
TSHR P16473 4/20 0.50
PARP10 Q53GL7 1/20 0.48
ALDH1A1 P00352 3/20 0.48
POLB P06746 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1B1 Q16678 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CYP2C19 P33261 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248077 0.91 LMNA (0.59) NPC1RAB9ALMNAF2CYP3A4
SCHEMBL8717537 0.89 LMNA (0.67) LMNAF2TSHRPARP10ALDH1A1
Hydrogen Peroxide SCHEMBL27952375 0.86 LMNA (0.70) LMNAF2CYP3A4TSHRPARP10
Benzene SCHEMBL27793442 0.86 LMNA (0.70) LMNAF2CYP3A4TSHRPARP10
SCHEMBL52413 0.86 LMNA (0.70) LMNAF2CYP3A4TSHRPARP10
SCHEMBL28446693 0.84 LMNA (0.53) NPC1RAB9ALMNAF2CYP3A4
SCHEMBL1417358 0.84 PBRM1 (0.52) NPC1RAB9ALMNAF2CYP3A4
Carbamic Acid SCHEMBL27556489 0.84 LMNA (0.61) NPC1RAB9ALMNAF2CYP3A4
SCHEMBL7050451 0.84 LMNA (0.67) LMNAF2CYP3A4TSHRPARP10
SCHEMBL1534569 0.84 LMNA (0.67) LMNAF2CYP3A4TSHRPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031557-B Synthesis method of 2- (4-aminophenyl) -5-aminobenzimidazole 湖南经世新材料有限责任公司 2023-10-13 CN claimed
CN-114031557-A Synthetic method of 2- (4-aminophenyl) -5-aminobenzimidazole 湖南经世新材料有限责任公司 2022-02-11 CN claimed
CN-107722047-B A kind of double-core Rare Earth Europium Complex luminescent material and its preparation method and application NANCHANG UNIVERSITY (CN) 2019-10-29 CN claimed
US-20180273819-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS COMPRISING TRIAMINES AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS LLC (US) 2018-09-27 US claimed
CN-107722047-A A kind of double-core Rare Earth Europium Complex luminescent material and its preparation method and application 南昌大学 2018-02-23 CN claimed
WO-2016179028-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS, LLC. (US) 2016-11-10 WO claimed
WO-2025015175-A2 HEATING, VENTILATION, AND AIR CONDITIONING (HVAC) SYSTEMS AND METHODS FOR USING SAME STASIS ENERGY GROUP, LLC (US) 2025-01-16 WO disclosed
US-20240254082-A1 Substituted Isoindoline-1, 3-diketone PDE4 Inhibitor and Pharmaceutical Application Thereof SUZHOU INTRAGRAND PHARMA CO., LTD (CN) 2024-08-01 US disclosed
EP-4385976-A1 SUBSTITUTED ISOINDOLIN-1,3-DIONE PDE4 INHIBITOR AND PHARMACEUTICAL USE THEREOF Suzhou Intragrand Pharma Co., Ltd (CN) 2024-06-19 EP disclosed
EP-3431547-B1 AQUEOUS DISPERSION, COMPRISING A CURABLE POLYESTER, RESOLE PHENOLIC RESINS AND WATER EASTMAN CHEM CO (US) 2023-10-25 EP disclosed
CN-114031557-B Synthesis method of 2- (4-aminophenyl) -5-aminobenzimidazole 湖南经世新材料有限责任公司 2023-10-13 CN disclosed
EP-3428231-B1 CURABLE POLYESTERS AND THERMOSETTING COMPOSITIONS CONTAINING RESOLE PHENOLIC RESINS EASTMAN CHEM CO (US) 2023-08-30 EP disclosed
CN-113527179-B Chain hydrocarbon substituted isoindoline-1, 3-diketone PDE4 inhibitor and pharmaceutical application thereof 苏州璞正医药有限公司 2023-07-07 CN disclosed
WO-2012000916-A1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-01-05 WO disclosed
US-7097856-B2 Anhydride prepared by combining benzylidene-2,2-bis(propanoic acid, N,N'-dicyclohexylcarbodiimide and an organic solvent forming a reaction mixuture containing formed anhydride THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-08-29 US disclosed
US-20020123609-A1 Dendrimeric support or carrier macromolecule THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-05 US disclosed
WO-2002026867-A2 DENDRIMERIC SUPPORT OR CARRIER MACROMOLECULE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-04-04 WO disclosed
US-4008175-A Organic acid anhydride-peroxydicarbonate composition PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-3985720-A Polymerization of ethylenically unsaturated monomer employing a catalyst system comprising dialkylpyrocarbonate, organic acid anhydride, alkaline reagent and H2 O2 PPG INDUSTRIES, INC. (US) 1976-10-12 US disclosed
US-3978032-A ALKALINE BUFFER, ANHYDRIDE, PERACID, ALKYL HALOFORMATE PPG INDUSTRIES, INC. (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254082-A1 Substituted Isoindoline-1, 3-diketone PDE4 Inhibitor and Pharmaceutical Application Thereof PDE4A, PDE4B, PDE3B NPC1 2550/4885RAB9A 2644/4885LMNA 2923/4885
US-20020123609-A1 Dendrimeric support or carrier macromolecule CD44, TSG101, BST2 NPC1 1660/4885RAB9A 2728/4885LMNA 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.