Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17419440 | 0.89 | BCL2 (0.45) | BCL2 | |
| SCHEMBL2507853 | 0.86 | ALDH3A1 (0.42) | ALDH3A1 | |
| SCHEMBL1958806 | 0.84 | ALDH3A1 (0.45) | BCL2ALDH3A1 | |
| SCHEMBL1957676 | 0.81 | BCL2 (0.47) | BCL2 | |
| SCHEMBL1956186 | 0.81 | BCL2 (0.49) | BCL2 | |
| SCHEMBL1957515 | 0.79 | BCL2 (0.61) | BCL2 | |
| SCHEMBL30314083 | 0.79 | BCL2 (0.61) | BCL2 | |
| SCHEMBL2506487 | 0.76 | BCL2 (0.42) | BCL2 | |
| SCHEMBL1742890 | 0.76 | MAPT (0.43) | — | |
| SCHEMBL1744608 | 0.75 | SLC6A2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376480-A2 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | claimed |
| WO-2010065865-A2 | BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | claimed |
| EP-2376480-A2 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010065865-A2 | BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |