Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731835 | 0.84 | TSHR (0.50) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL20897631 | 0.78 | VCP (0.53) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29902925 | 0.78 | ALDH1A1 (0.67) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL22552141 | 0.78 | ALDH1A1 (0.67) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7829981 | 0.76 | ERN1 (0.58) | LMNAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL30790370 | 0.76 | ERN1 (0.58) | LMNAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL1721212 | 0.76 | XDH (0.43) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14153758 | 0.75 | KMT2A (0.60) | LMNAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL1720931 | 0.75 | MAPT (0.40) | MEN1KMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL30849028 | 0.74 | XDH (0.45) | LMNAMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588453-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003189-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2012-01-05 | — | — | WO | disclosed |