Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | FES | P07332 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108914 | 0.80 | PLK4 (0.53) | JAK2MAP4K4KDRFGFR1PLK4 | |
| SCHEMBL23277107 | 0.78 | JAK2 (0.51) | JAK2METAP2MAP4K4PTGS1PTGS2 | |
| SCHEMBL29730261 | 0.78 | JAK2 (0.51) | JAK2METAP2MAP4K4PTGS1PTGS2 | |
| SCHEMBL27961301 | 0.77 | MAP4K4 (0.70) | JAK2METAP2MAP4K4FGFR1MINK1 | |
| SCHEMBL29973626 | 0.77 | MAP4K4 (0.70) | JAK2METAP2MAP4K4FGFR1MINK1 | |
| SCHEMBL6069781 | 0.75 | PTGS2 (0.49) | JAK2PTGS1PTGS2 | |
| SCHEMBL6069777 | 0.75 | PTGS2 (0.63) | PTGS1PTGS2 | |
| SCHEMBL28146261 | 0.74 | FFAR4 (0.34) | MAP4K4KDRPTGS1PTGS2 | |
| SCHEMBL29763127 | 0.74 | ALDH1A1 (0.54) | METAP2MAP4K4CSNK2A1MAPK1CYP2A6 | |
| SCHEMBL8638226 | 0.74 | ALDH1A1 (0.54) | METAP2MAP4K4CSNK2A1MAPK1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022267901-A1 | ORGANIC COMPOUND, ELECTRONIC COMPONENT. AND ELECTRONIC DEVICE | 陕西莱特光电材料股份有限公司 | 2022-12-29 | — | — | WO | disclosed |