Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24808064 | 0.97 | KDM4E (0.40) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL24808190 | 0.89 | KDM4E (0.52) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL24808465 | 0.87 | KDM4E (0.49) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL6730707 | 0.83 | ACSS2 (0.39) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7637380 | 0.79 | KDM4E (0.44) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL30583320 | 0.74 | POLB (0.41) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL21632144 | 0.72 | GAA (0.47) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL22790508 | 0.72 | TLR7 (0.48) | GAAKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL842305 | 0.71 | ATM (0.42) | GAAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL8571971 | 0.71 | KDM4E (0.43) | GAAKDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411421-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF | CHOU, YU-CHENG (TW) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411421-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF | TLR7, TLR8, TLR6 | GAA 3930/4885KDM4E 986/4885ALDH1A1 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.