Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23132278 | 0.90 | MCHR1 (0.45) | FAAHALDH1A1TAAR1HIF1ATP53 | |
| SCHEMBL24809696 | 0.89 | FAAH (0.39) | FAAHALDH1A1SMN1; SMN2HPGDHIF1A | |
| SCHEMBL29817652 | 0.89 | FAAH (0.39) | FAAHALDH1A1SMN1; SMN2HPGDHIF1A | |
| SCHEMBL24809404 | 0.86 | ALDH1A1 (0.47) | FAAHALDH1A1SMN1; SMN2HPGDTAAR1 | |
| SCHEMBL24810551 | 0.84 | KDM4E (0.38) | ALDH1A1SMN1; SMN2HPGDTAAR1TP53 | |
| SCHEMBL29817737 | 0.80 | CYP2C9 (0.54) | ALDH1A1SMN1; SMN2HIF1ARAB9ANPC1 | |
| SCHEMBL24811030 | 0.80 | CYP2C9 (0.54) | ALDH1A1SMN1; SMN2HIF1ARAB9ANPC1 | |
| SCHEMBL24810703 | 0.80 | RAB9A (0.51) | ALDH1A1SMN1; SMN2HIF1ARAB9ANPC1 | |
| SCHEMBL24809675 | 0.79 | ASAH1 (0.50) | FAAHHPGDRAB9ANPC1 | |
| SCHEMBL24809408 | 0.79 | HIF1A (0.46) | ALDH1A1SMN1; SMN2HPGDHIF1AAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411388-A1 | SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL R&D INVEST S A (PT) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411388-A1 | SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GAA, CLN6 | FAAH 368/4885ALDH1A1 1398/4885SMN1; SMN2 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.