SCHEMBL24810451

SCHEMBL24810451

c1ccc(-n2c3ccccc3c3ccc(-c4cccc5c4c4ccccc4n5-c4ccc(-c5ccc(-c6cccc7oc8ccccc8c67)cc5)cc4)cc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HDAC4 P56524 1/20 0.36
ALOX5 P09917 1/20 0.33
BACE1 P56817 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGER4 P35408 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24812234 1.00 KDM4E (0.41) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL26788458 1.00 KDM4E (0.41) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL26788385 1.00 KDM4E (0.41) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL24810499 0.99 KDM4E (0.42) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL24811983 0.99 KDM4E (0.42) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL24810871 0.98 KDM4E (0.38) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL24810490 0.96 KDM4E (0.37) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL24810369 0.94 KDM4E (0.44) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL26788411 0.94 KDM4E (0.44) KDM4EATML3MBTL1HDAC4ALOX5
SCHEMBL24811979 0.93 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-20230371373-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE ldemitsu Kosan Co.,Ltd. (JP) 2023-11-16 US disclosed
US-20230371373-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE ldemitsu Kosan Co.,Ltd. (JP) 2023-11-16 US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 KDM4E 3416/4885ATM 3436/4885L3MBTL1 1876/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 KDM4E 1340/4885ATM 3092/4885L3MBTL1 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.