Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462345 | 0.81 | FDPS (0.55) | FDPSHPGDPPARGPPARDPPARA | |
| SCHEMBL12016738 | 0.80 | FDPS (0.54) | FDPSPPARGPPARDPPARAHIF1A | |
| SCHEMBL1766008 | 0.80 | FDPS (0.54) | FDPSHPGDPPARGPPARDPPARA | |
| SCHEMBL7358235 | 0.78 | PDE4B (0.46) | FDPSHPGDDRD2DRD4PDE4B | |
| SCHEMBL7350554 | 0.77 | PDE4B (0.46) | DRD2DRD4PDE4BKMT2AL3MBTL1 | |
| SCHEMBL25139486 | 0.77 | PDE4A (0.47) | HPGDPDE4BKMT2AKDM4E | |
| SCHEMBL12344806 | 0.77 | GAA (0.57) | FDPSHPGDDRD2DRD4KMT2A | |
| SCHEMBL8238025 | 0.77 | PPARG (0.59) | FDPSHPGDPPARGPPARDPPARA | |
| SCHEMBL670305 | 0.77 | PPARG (0.59) | FDPSHPGDPPARGPPARDPPARA | |
| SCHEMBL25139578 | 0.75 | KMT2A (0.56) | HPGDPDE4BKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272106-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |