Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12016738 | 0.92 | FDPS (0.54) | FDPSKDM4EPPARGPPARDPPARA | |
| SCHEMBL11951555 | 0.87 | FDPS (0.50) | FDPSKDM4EPPARGPPARDPPARA | |
| SCHEMBL7333971 | 0.86 | SMPD1 (0.50) | FDPSPPARGPPARDPPARASMN1; SMN2 | |
| SCHEMBL1766008 | 0.86 | FDPS (0.54) | FDPSKDM4EPPARGPPARDPPARA | |
| SCHEMBL16955884 | 0.84 | FDPS (0.48) | FDPSKDM4EPPARGPPARDPPARA | |
| SCHEMBL8238025 | 0.82 | PPARG (0.59) | FDPSPPARGPPARDPPARAHPGD | |
| SCHEMBL670305 | 0.82 | PPARG (0.59) | FDPSPPARGPPARDPPARAHPGD | |
| SCHEMBL19790002 | 0.81 | KDM4E (0.47) | FDPSKDM4EHPGDHSD17B10POLB | |
| SCHEMBL12446451 | 0.81 | FDPS (0.46) | FDPSKDM4EPPARGPPARDPPARA | |
| SCHEMBL24812331 | 0.81 | FDPS (0.49) | FDPSKDM4EPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032532-A1 | \"PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF\ | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | claimed |