Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176363 | 0.82 | LMNA (0.71) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL6653369 | 0.82 | POLB (0.59) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL8971941 | 0.82 | POLB (0.59) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL8971725 | 0.82 | POLB (0.59) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL7211528 | 0.81 | HPGD (0.57) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL8998577 | 0.81 | POLB (0.54) | POLBTDP1HPGDALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8998584 | 0.81 | POLB (0.57) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL26169734 | 0.81 | POLB (0.57) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL8998493 | 0.81 | POLB (0.54) | POLBTDP1HPGDALDH1A1LMNA | |
| SCHEMBL25616720 | 0.81 | POLB (0.66) | POLBTDP1HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |