SCHEMBL24813196

SCHEMBL24813196

c1ccc2c(c1)oc1ccc(-c3ccc4oc5ccc(-c6ccc(-c7ccc(-n8c9ccccc9c9ccccc98)cc7)cc6)cc5c4c3)cc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
NPC1 O15118 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
RAB9A P51151 1/20 0.45
PLA2G2A P14555 5/20 0.42
PLA2G4A P47712 5/20 0.42
AHR P35869 2/20 0.41
HDAC4 P56524 1/20 0.39
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24173831 1.00 KDM4E (0.47) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL24173820 1.00 KDM4E (0.47) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL19238736 1.00 KDM4E (0.47) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL804745 0.97 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL16171583 0.97 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL11987361 0.97 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL24811820 0.97 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL804772 0.97 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL16804580 0.97 KDM4E (0.50) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL24173841 0.96 PLA2G2A (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 KDM4E 3416/4885ATM 3436/4885L3MBTL1 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.