Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625194 | 0.89 | KDM4E (0.75) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL30048580 | 0.86 | KDM4E (0.79) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL8581146 | 0.86 | KDM4E (0.79) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL6951691 | 0.84 | MTNR1A (0.61) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL8581128 | 0.84 | MTNR1A (0.61) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL4854372 | 0.84 | HTR2A (0.63) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL25139741 | 0.83 | MTNR1A (0.60) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL25277741 | 0.82 | HTR6 (0.61) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL25139838 | 0.81 | PARP15 (0.45) | MTNR1AMTNR1BKDM4EHTR2A | |
| SCHEMBL25139540 | 0.81 | HTR2A (0.55) | MTNR1AMTNR1BKDM4EHTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. | 2023-04-20 | — | — | US | disclosed |
| WO-2022272106-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CDK2, CDK20, CDK2AP2 | MTNR1A 2726/4885MTNR1B 2417/4885KDM4E 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.