Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139741 | 0.87 | MTNR1A (0.60) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL30048580 | 0.87 | KDM4E (0.79) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL8581146 | 0.87 | KDM4E (0.79) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL4854372 | 0.86 | HTR2A (0.63) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL6951691 | 0.86 | MTNR1A (0.61) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL24814482 | 0.84 | MTNR1A (0.60) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL25277741 | 0.83 | HTR6 (0.61) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL8377078 | 0.82 | HTR2A (0.69) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL25271689 | 0.80 | MTNR1A (0.55) | MTNR1AMTNR1BKDM4EHTR2AMEN1 | |
| SCHEMBL2686551 | 0.80 | KDM4E (0.77) | MTNR1AMTNR1BKDM4EHTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |