Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.35 |
| ▸ | HRH1 | P35367 | 6/20 | 0.33 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047454 | 1.00 | HTR6 (0.35) | HTR6HRH1DHODHHTR3EHTR3B | |
| SCHEMBL23576692 | 0.89 | DHODH (0.36) | HTR6DHODH | |
| SCHEMBL29909342 | 0.89 | DHODH (0.36) | HTR6DHODH | |
| SCHEMBL30047169 | 0.85 | DHODH (0.32) | HTR6DHODH | |
| SCHEMBL30047655 | 0.83 | MAPT (0.33) | — | |
| SCHEMBL24813109 | 0.83 | MAPT (0.33) | — | |
| SCHEMBL24813112 | 0.83 | MAPT (0.36) | — | |
| SCHEMBL30047261 | 0.83 | MAPT (0.36) | — | |
| SCHEMBL24815997 | 0.82 | ADORA3 (0.32) | HTR6HRH1DHODH | |
| SCHEMBL24815998 | 0.82 | PTAFR (0.31) | HTR6HRH1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |