SCHEMBL248151

SCHEMBL248151

CN1CCN(CCCN)CC1

nearest known ligand 0.79

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ALOX15 P16050 1/20 0.52
SIGMAR1 Q99720 3/20 0.48
CYP2D6 P10635 1/20 0.48
PAOX Q6QHF9 1/20 0.47
ACE2 Q9BYF1 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7427988 0.97 KEAP1 (0.54) KEAP1SMN1; SMN2ALOX15SIGMAR1CYP2D6
SCHEMBL856408 0.92 SIGMAR1 (0.50) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
SCHEMBL3964262 0.91 CHKA (0.49) KEAP1SMN1; SMN2ALOX15SIGMAR1CYP2D6
SCHEMBL31092072 0.90 PAOX (0.53) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
Hydrochloric Acid SCHEMBL27751183 0.90 SIGMAR1 (0.48) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
Hydrochloric Acid SCHEMBL3677133 0.90 SIGMAR1 (0.48) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
SCHEMBL3970460 0.90 PAOX (0.53) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
SCHEMBL26488666 0.90 PAOX (0.53) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
SCHEMBL22564678 0.90 PAOX (0.53) KEAP1SMN1; SMN2ALOX15SIGMAR1PAOX
SCHEMBL1616800 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2423 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
US-12508318-B2 UV light-responsive hyperbranched poly-β-amino ester having high-efficiency gene delivery ability and preparation method and application thereof SOOCHOW UNIVERSITY (CN) 2025-12-30 US claimed
CN-119792544-A Nano carrier and preparation method and application thereof 山东大学 2025-04-11 CN claimed
CN-119708521-A Preparation method and application of lung organ targeted branched poly (beta-amino ester) based mRNA (messenger ribonucleic acid) compound nano particles 复旦大学附属儿科医院 2025-03-28 CN claimed
WO-2025059107-A1 DEGRADABLE, BRANCHED LIPID COMPOUNDS, METHODS OF PREPARATION THEREOF, LIPID NANOPARTICLES (LNPS) COMPRISING THE SAME, AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-03-20 WO claimed
CN-119506361-A PBAE-DOPE-PEG2000 polymer-lipid nanocomposite and preparation method and application thereof 山东大学 2025-02-25 CN claimed
CN-118561797-B Benzopyran antibacterial peptide mimics with broad-spectrum antibacterial activity, and preparation method and application thereof 聊城大学 2025-02-18 CN claimed
CN-119431775-A Branched fluorine-containing poly (beta-amino ester) and preparation method and application thereof 北京大学 2025-02-14 CN claimed
CN-119409987-A Hyperbranched poly (beta-amino ester), preparation method, composite nanoparticle and application 复旦大学附属儿科医院 2025-02-11 CN claimed
CN-119161574-A Functional star poly (beta-amino ester), preparation method thereof and mRNA delivery application 上海艾迪特基因科技有限公司 2024-12-20 CN claimed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO claimed
WO-1996015118-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1996-05-23 WO claimed
US-5519024-A CELL ADHESION INHIBITOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-05-21 US claimed
EP-0375451-A2 Compounds having a renin-inhibiting activity BEECHAM GROUP PLC (GB) 1990-06-27 EP claimed
US-4919685-A CONTAINING AS STORAGE STABILIZER A COPOLYMER GRAFTED WITH ALIPHATIC AND/OR ALIPHATIC POLYAMINE SUCCINIMIDE TEXACO INC. (US) 1990-04-24 US claimed
EP-0025142-B1 POLYQUATERNARY AMMONIUM COMPOUNDS, THEIR PREPARATION, THEIR USE IN PAPER MANUFACTURING AND PAPER TREATING AGENTS CONTAINING THEM BAYER AG (DE) 1984-08-08 EP claimed
US-4423194-A IMIDATION OF COPOLYMERS OF MALEIC ANHYDRIDE AND AN OLEFIN WITH AN AMINE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US claimed
EP-0025142-A1 Polyquaternary ammonium compounds, their preparation, their use in paper manufacturing and paper treating agents containing them BAYER AG (DE) 1981-03-18 EP claimed
EP-0021580-A1 Sulphonamide derivatives, a process for their preparation and their use as medicines BEECHAM - WUELFING GmbH & Co. KG (DE) 1981-01-07 EP claimed
US-4122265-A APPETITE SUPPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1978-10-24 US claimed