SCHEMBL26488666

SCHEMBL26488666

CN1CCN(CCCCCCN)CC1

nearest known ligand 0.76

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.53
SIGMAR1 Q99720 2/20 0.48
ALOX15 P16050 1/20 0.48
GNAI3 P08754 1/20 0.47
GNAO1 P09471 1/20 0.47
GNAI1 P63096 1/20 0.47
KEAP1 Q14145 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31092072 1.00 PAOX (0.53) PAOXSIGMAR1ALOX15GNAI3GNAO1
SCHEMBL3970460 1.00 PAOX (0.53) PAOXSIGMAR1ALOX15GNAI3GNAO1
SCHEMBL22564678 1.00 PAOX (0.53) PAOXSIGMAR1ALOX15GNAI3GNAO1
Hydrochloric Acid SCHEMBL20507343 0.98 PAOX (0.52) PAOXSIGMAR1ALOX15GNAI3GNAO1
SCHEMBL856408 0.98 SIGMAR1 (0.50) PAOXSIGMAR1ALOX15GNAI3GNAO1
Hydrochloric Acid SCHEMBL27751183 0.95 SIGMAR1 (0.48) PAOXSIGMAR1ALOX15GNAI3GNAO1
Hydrochloric Acid SCHEMBL3677133 0.95 SIGMAR1 (0.48) PAOXSIGMAR1ALOX15GNAI3GNAO1
SCHEMBL25344455 0.92 HRH3 (0.48) PAOXSIGMAR1ALOX15GNAI3GNAO1
SCHEMBL248151 0.90 KEAP1 (0.56) PAOXSIGMAR1ALOX15KEAP1SMN1; SMN2
SCHEMBL1615521 0.90 ALOX15 (0.58) SIGMAR1ALOX15KEAP1SMN1; SMN2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652225-A Phosphorus-free degradable CaSO (CaSOx resistance)4Small molecular scale inhibitor as well as preparation method and application thereof 石家庄铁道大学 2024-09-17 CN disclosed
WO-2024140595-A1 TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 珂阑(上海)医药科技有限公司 2024-07-04 WO disclosed
CN-118255685-A Tricyclic compound, pharmaceutical composition and application thereof 珂阑(上海)医药科技有限公司 2024-06-28 CN disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
WO-2023071601-A1 DESLORATADINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 天津市昕晨投资发展有限公司 2023-05-04 WO disclosed
CN-101827851-A 5-cyano-thienopyridines for the treatment of tumors MERCK PATENT GMBH 2010-09-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 PAOX 1159/4885SIGMAR1 2858/4885ALOX15 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.