⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380957 | 0.95 | — | — | |
| SCHEMBL12292038 | 0.77 | — | — | |
| SCHEMBL23155079 | 0.72 | — | — | |
| SCHEMBL3431415 | 0.71 | POLB (0.31) | — | |
| SCHEMBL21899209 | 0.71 | — | — | |
| SCHEMBL19057205 | 0.69 | LMNA (0.32) | — | |
| SCHEMBL20434567 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL16541993 | 0.67 | — | — | |
| SCHEMBL16417298 | 0.65 | — | — | |
| SCHEMBL25156605 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |