Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814740 | 0.88 | NLRP3 (0.35) | NAMPTDPP9DPP8 | |
| SCHEMBL29987551 | 0.87 | MAOB (0.39) | NAMPT | |
| SCHEMBL24817127 | 0.86 | MAOB (0.40) | NAMPTDPP4 | |
| SCHEMBL26845908 | 0.86 | DPP8 (0.40) | NAMPTDPP9DPP8DPP4DPP7 | |
| SCHEMBL24815669 | 0.86 | SMN1; SMN2 (0.42) | NAMPT | |
| SCHEMBL29986905 | 0.86 | SMN1; SMN2 (0.42) | NAMPT | |
| SCHEMBL24814391 | 0.84 | RYR2 (0.43) | NAMPTROCK1 | |
| SCHEMBL24815670 | 0.83 | NLRP3 (0.35) | — | |
| SCHEMBL24814401 | 0.83 | DPP7 (0.43) | NAMPTDPP7 | |
| SCHEMBL24815798 | 0.82 | NAMPT (0.42) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827629-B2 | CDGSH iron sulfur domain 2 activators and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2023-11-28 | — | — | US | disclosed |
| US-11827629-B2 | CDGSH iron sulfur domain 2 activators and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2023-11-28 | — | — | US | disclosed |
| US-20220411418-A1 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-29 | — | — | US | disclosed |
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411418-A1 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | CISD2, CISD1, FECH | NAMPT 2850/4885DPP9 4490/4885DPP8 4457/4885 |
| US-11827629-B2 | CDGSH iron sulfur domain 2 activators and use thereof | CISD2, CISD1, FECH | NAMPT 2850/4885DPP9 4490/4885DPP8 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.