Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816831 | 0.85 | CRBN (0.48) | IKZF2IKZF1CRBN | |
| SCHEMBL24818130 | 0.85 | CRBN (0.48) | IKZF2IKZF1CRBN | |
| SCHEMBL24819318 | 0.76 | CRBN (0.56) | IKZF2IKZF1CRBN | |
| SCHEMBL24819319 | 0.72 | IKZF2 (0.44) | IKZF2IKZF1CRBN | |
| SCHEMBL23876990 | 0.69 | CRBN (0.40) | IKZF2IKZF1CRBN | |
| SCHEMBL27143832 | 0.69 | CRBN (0.53) | IKZF2IKZF1CRBN | |
| SCHEMBL27143837 | 0.69 | CRBN (0.53) | IKZF2IKZF1CRBN | |
| SCHEMBL30718612 | 0.69 | CRBN (0.53) | IKZF2IKZF1CRBN | |
| SCHEMBL24817738 | 0.69 | CRBN (0.58) | IKZF2CRBN | |
| SCHEMBL20231482 | 0.69 | CRBN (0.58) | IKZF2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |