Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299684 | 0.80 | DHODH (0.46) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL12109671 | 0.79 | DRD4 (0.47) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL19103550 | 0.78 | VSIR (0.42) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL12109658 | 0.77 | MAPT (0.45) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL6214425 | 0.75 | GAA (0.47) | MAPTKMT2AMEN1GAAVSIR | |
| SCHEMBL889001 | 0.75 | HSD17B10 (0.47) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL24818519 | 0.74 | CFTR (0.33) | MAPTKDM4EPOLBHPGD | |
| SCHEMBL12213873 | 0.74 | ALDH1A1 (0.46) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL11366200 | 0.73 | HSD17B10 (0.46) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL24821636 | 0.73 | RAB9A (0.44) | MAPTKDM4EPOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |