Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152844 | 0.88 | CBLB (0.38) | IDH1CBLB | |
| SCHEMBL30153003 | 0.84 | CD274 (0.35) | KCNH2VSIRMAP3K5 | |
| SCHEMBL24818678 | 0.84 | CD274 (0.35) | KCNH2VSIRMAP3K5 | |
| SCHEMBL30152678 | 0.80 | GUSB (0.36) | VSIR | |
| SCHEMBL24818859 | 0.80 | GUSB (0.36) | VSIR | |
| SCHEMBL24818813 | 0.80 | GUSB (0.36) | VSIR | |
| SCHEMBL24819848 | 0.79 | VSIR (0.39) | VSIR | |
| SCHEMBL30152909 | 0.78 | VSIR (0.38) | KCNH2VSIR | |
| SCHEMBL24818669 | 0.78 | VSIR (0.38) | KCNH2VSIR | |
| SCHEMBL24821952 | 0.75 | CBLB (0.34) | KCNH2CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |