Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | CEPT1 | Q9Y6K0 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153245 | 1.00 | ESR2 (0.34) | ESR2ESR1VSIRCBLBCEPT1 | |
| SCHEMBL24819899 | 0.89 | CBLB (0.39) | VSIRCBLBHPGDP2RX7HSD11B1 | |
| SCHEMBL30152763 | 0.88 | VSIR (0.34) | VSIRCBLBHPGDCETPSCN9A | |
| SCHEMBL24818674 | 0.87 | VSIR (0.40) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL24818892 | 0.87 | VSIR (0.36) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL30152764 | 0.87 | CETP (0.37) | ESR2ESR1VSIRCBLBHPGD | |
| SCHEMBL24818753 | 0.87 | VSIR (0.34) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL24819864 | 0.87 | CETP (0.37) | ESR2ESR1VSIRCBLBHPGD | |
| SCHEMBL24819724 | 0.87 | VSIR (0.33) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL24818726 | 0.87 | HPGD (0.37) | VSIRCBLBHPGDCETPSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |