Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820065 | 0.95 | VSIR (0.34) | VSIRCBLBHPGDLMNAGAA | |
| SCHEMBL30152989 | 0.95 | VSIR (0.34) | VSIRCBLBHPGDLMNAGAA | |
| SCHEMBL30152763 | 0.94 | VSIR (0.34) | VSIRCBLBHPGDCETPSCN9A | |
| SCHEMBL30153178 | 0.93 | VSIR (0.34) | VSIRHPGDLMNAGAA | |
| SCHEMBL24821892 | 0.93 | VSIR (0.34) | VSIRHPGDLMNAGAA | |
| SCHEMBL24819724 | 0.92 | VSIR (0.33) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL24820501 | 0.92 | CBLB (0.37) | VSIRCBLBCETPSCN9AS1PR1 | |
| SCHEMBL30153254 | 0.92 | CBLB (0.37) | VSIRCBLBCETPSCN9AS1PR1 | |
| SCHEMBL24818959 | 0.90 | VSIR (0.36) | VSIRHPGDLMNAGAA | |
| SCHEMBL24819012 | 0.90 | HPGD (0.40) | VSIRHPGDCETPLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |