Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818753 | 0.92 | VSIR (0.34) | VSIRCBLBHSD11B1HPGDCETP | |
| SCHEMBL30152763 | 0.90 | VSIR (0.34) | VSIRCBLBHPGDCETP | |
| SCHEMBL24818951 | 0.87 | ESR2 (0.34) | VSIRCBLBHSD11B1HPGDCETP | |
| SCHEMBL30153245 | 0.87 | ESR2 (0.34) | VSIRCBLBHSD11B1HPGDCETP | |
| SCHEMBL24819899 | 0.87 | CBLB (0.39) | VSIRCBLBHSD11B1HPGDP2RX7 | |
| SCHEMBL30152989 | 0.87 | VSIR (0.34) | VSIRCBLBHPGD | |
| SCHEMBL24820065 | 0.87 | VSIR (0.34) | VSIRCBLBHPGD | |
| SCHEMBL30153163 | 0.85 | VSIR (0.39) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL24818892 | 0.85 | VSIR (0.36) | VSIRCBLBHPGDCETPP2RX7 | |
| SCHEMBL24819864 | 0.85 | CETP (0.37) | VSIRCBLBHSD11B1HPGDCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |