Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152867 | 1.00 | MAPT (0.38) | MAPTSMN1; SMN2RAB9ATP53ALOX5AP | |
| SCHEMBL30792132 | 1.00 | MAPT (0.38) | MAPTSMN1; SMN2RAB9ATP53ALOX5AP | |
| SCHEMBL30792049 | 0.91 | AGPAT2 (0.38) | MAPTSMN1; SMN2RAB9ATP53HDAC6 | |
| SCHEMBL24820737 | 0.91 | AGPAT2 (0.38) | MAPTSMN1; SMN2RAB9ATP53HDAC6 | |
| SCHEMBL30792199 | 0.89 | CBLB (0.41) | MAPTSMN1; SMN2RAB9ATP53HDAC6 | |
| SCHEMBL24820567 | 0.89 | CBLB (0.41) | MAPTSMN1; SMN2RAB9ATP53HDAC6 | |
| SCHEMBL30153017 | 0.89 | CBLB (0.41) | MAPTSMN1; SMN2RAB9ATP53HDAC6 | |
| SCHEMBL24820121 | 0.89 | HPGD (0.33) | MAPTSMN1; SMN2RAB9ATP53KDM4E | |
| SCHEMBL24820582 | 0.89 | MAP3K5 (0.34) | MAPTSMN1; SMN2RAB9AKDM4ENPC1 | |
| SCHEMBL30152670 | 0.89 | HPGD (0.33) | MAPTSMN1; SMN2RAB9ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |