Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792049 | 1.00 | AGPAT2 (0.38) | AGPAT2MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL30792132 | 0.91 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL30152867 | 0.91 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL24818763 | 0.91 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL30792199 | 0.89 | CBLB (0.41) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL24820567 | 0.89 | CBLB (0.41) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL30153017 | 0.89 | CBLB (0.41) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL24820138 | 0.88 | MAP3K5 (0.34) | SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL30153076 | 0.88 | MAP3K5 (0.34) | SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL30792001 | 0.88 | MAP3K5 (0.34) | SMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |