Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816881 | 0.92 | FFAR4 (0.36) | SLC6A4SLC6A3FFAR4HTTALDH1A1 | |
| SCHEMBL20766650 | 0.85 | KDM4E (0.42) | SLC6A4SLC6A3FFAR4HTTALDH1A1 | |
| SCHEMBL24744883 | 0.80 | MTNR1A (0.34) | FFAR4ALDH1A1MAPTNPSR1MTNR1A | |
| SCHEMBL18878157 | 0.79 | CES2 (0.39) | SLC6A4SLC6A3ALDH1A1MAPTLMNA | |
| SCHEMBL24571901 | 0.79 | ALDH1A1 (0.43) | SLC6A4SLC6A3HTTALDH1A1MAPT | |
| SCHEMBL31727123 | 0.79 | ALDH1A1 (0.43) | SLC6A4SLC6A3HTTALDH1A1MAPT | |
| SCHEMBL30296812 | 0.78 | SOS1 (0.41) | SLC6A4SLC6A3ALDH1A1MAPTKMT2A | |
| SCHEMBL14719178 | 0.78 | KDM4E (0.37) | SLC6A4SLC6A3FFAR4HTTALDH1A1 | |
| SCHEMBL3410570 | 0.78 | SOS1 (0.41) | SLC6A4SLC6A3ALDH1A1MAPTKMT2A | |
| SCHEMBL19305473 | 0.77 | FFAR4 (0.36) | SLC6A4SLC6A3FFAR4HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |