Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152749 | 1.00 | CBLB (0.43) | CBLBSCN9AC1RHSD11B1TP53 | |
| SCHEMBL24819899 | 0.91 | CBLB (0.39) | CBLBSCN9AHSD11B1TP53MAPT | |
| SCHEMBL24818731 | 0.90 | NPC1 (0.40) | CBLBSCN9AHSD11B1TP53MAPT | |
| SCHEMBL24818812 | 0.87 | CBLB (0.39) | CBLBVSIRNOTUM | |
| SCHEMBL30153053 | 0.87 | CBLB (0.39) | CBLBVSIRNOTUM | |
| SCHEMBL30153127 | 0.87 | S1PR1 (0.37) | CBLBSCN9AVSIR | |
| SCHEMBL24819786 | 0.87 | S1PR1 (0.37) | CBLBSCN9AVSIR | |
| SCHEMBL24819872 | 0.86 | CETP (0.39) | CBLBSCN9ATP53MAPTVSIR | |
| SCHEMBL24820501 | 0.86 | CBLB (0.37) | CBLBSCN9AHSD11B1TP53MAPT | |
| SCHEMBL30153254 | 0.86 | CBLB (0.37) | CBLBSCN9AHSD11B1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |