Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 4/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30999280 | 1.00 | GABRG2 (0.40) | GABRG2GABRB3GABRA5GABRA3MEN1 | |
| SCHEMBL29920328 | 0.85 | GAA (0.39) | GABRG2GABRB3GABRA5GABRA3MEN1 | |
| SCHEMBL30792272 | 0.84 | ALDH1A1 (0.49) | PIM1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29193077 | 0.82 | KDM4E (0.40) | GABRG2GABRB3GABRA5GABRA3MEN1 | |
| SCHEMBL24820283 | 0.82 | IDO1 (0.47) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL24819955 | 0.82 | BRD4 (0.47) | RAB9ATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL29920482 | 0.82 | BRD4 (0.47) | RAB9ATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL27085998 | 0.82 | KDM4E (0.42) | GABRG2GABRB3GABRA5GABRA3MEN1 | |
| SCHEMBL24818871 | 0.80 | CBLB (0.52) | GABRG2GABRB3GABRA5GABRA3MEN1 | |
| SCHEMBL30825379 | 0.80 | BRD4 (0.39) | GABRG2GABRB3GABRA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |