Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 5/20 | 0.43 |
| ▸ | FNTB | P49356 | 5/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792128 | 0.85 | HSD11B1 (0.50) | FNTAFNTBHSD11B1LMNAGAA | |
| SCHEMBL24818953 | 0.85 | LMNA (0.43) | IDO1FNTAFNTBNOTUMMEN1 | |
| SCHEMBL30792272 | 0.84 | ALDH1A1 (0.49) | HSD11B1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL24819952 | 0.82 | GABRG2 (0.40) | MEN1KMT2ALMNAGAAMAOB | |
| SCHEMBL30999280 | 0.82 | GABRG2 (0.40) | MEN1KMT2ALMNAGAAMAOB | |
| SCHEMBL29920482 | 0.82 | BRD4 (0.47) | RAB9ATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL24819955 | 0.82 | BRD4 (0.47) | RAB9ATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL24820316 | 0.81 | ADORA2A (0.39) | KMT2AHSD11B1LMNAGAAKDM4E | |
| SCHEMBL30792025 | 0.81 | ADORA2A (0.39) | KMT2AHSD11B1LMNAGAAKDM4E | |
| SCHEMBL27086306 | 0.80 | FNTA (0.40) | IDO1FNTAFNTBHSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |