Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24821928 | 0.77 | ALDH1A1 (0.40) | LTA4HCD274PDCD1HTR1A | |
| SCHEMBL24820563 | 0.77 | ALDH1A1 (0.40) | LTA4HCD274PDCD1HTR1A | |
| SCHEMBL22105522 | 0.72 | SSTR3 (0.54) | LTA4HCD274PDCD1PDCD1LG2SSTR3 | |
| SCHEMBL9791812 | 0.72 | LTA4H (0.58) | LTA4HCD274PDCD1PDCD1LG2 | |
| SCHEMBL13634413 | 0.72 | LTA4H (0.58) | LTA4HCD274PDCD1PDCD1LG2 | |
| SCHEMBL108594 | 0.72 | ERCC1 (0.58) | ERCC1ERCC4SSTR3 | |
| SCHEMBL15818134 | 0.72 | LTA4H (0.58) | LTA4HCD274PDCD1PDCD1LG2 | |
| SCHEMBL1847853 | 0.72 | LTA4H (0.58) | LTA4HCD274PDCD1PDCD1LG2 | |
| SCHEMBL8231045 | 0.72 | ERCC1 (0.58) | ERCC1ERCC4SSTR3 | |
| SCHEMBL139478 | 0.72 | ERCC1 (0.58) | ERCC1ERCC4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |